ANTIBODIES AGAINST PD-1 FOR TREATMENT OF LUNG CANCER Russian patent published in 2022 - IPC C07K16/28 A61K39/395 A61P35/00 

Abstract RU 2771759 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to methods for the treatment of lung cancer. Methods include the selection of a patient with non-small cell lung cancer, where patient’s tumor tissue expresses PD-L1 in ≥50% of tumor cells, and the patient is not tested as positive relatively to mutations of an epidermal growth factor receptor (EGFR), translocations of anaplastic lymphoma kinase (ALK) and/or fusions of ROS1, as well as the injection to the patient of therapeutically effective amount of an antibody specifically binding to PD-1.

EFFECT: invention is effective for the treatment of non-small cell lung cancer.

28 cl, 14 dwg, 13 tbl, 15 ex

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RU 2 771 759 C2

Authors

Rietschel, Petra

Lowy, Israel

Dates

2022-05-11Published

2018-02-20Filed