METHODS OF TREATING CERVICAL CANCER BY ADMINISTERING INHIBITOR PD-1 Russian patent published in 2025 - IPC C07K16/28 A61K39/395 A61P35/00 

Abstract RU 2833461 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to a method of treating or inhibiting tumour growth in a patient with cervical cancer, involving selecting a patient with recurrent or metastatic cervical cancer and with disease progression with underlying or following platinum-based chemotherapy and administering to the patient an antibody or an antigen-binding fragment thereof, which specifically binds to programmed cell death protein 1 (PD-1), as a monotherapy in dose of 350 mg every 3 weeks. Also disclosed is a method for improving overall survival of a patient with cervical cancer, involving selecting a patient with recurrent or metastatic cervical cancer and progression of the disease with underlying or after platinum-based chemotherapy and administering an antibody or an antigen-binding fragment thereof, which specifically binds to programmed cell death protein 1 (PD-1), as monotherapy in dose of 350 mg every 3 weeks.

EFFECT: invention is effective for treating or inhibiting tumour growth in a patient with recurrent or metastatic cervical cancer and disease progression with underlying or following platinum-based chemotherapy.

33 cl, 9 dwg, 31 tbl, 5 ex

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RU 2 833 461 C1

Authors

Fury, Matthew, G.

Lowy, Israel

Mathias, Melissa, Divya

Yama-Dang, Nazumi, Alice

Fury, Wen

Dates

2025-01-21Published

2021-05-25Filed