COMBINATION OF TRIFLURIDINE/TIPIRACIL HYDROCHLORIDE, ANTITUMOR PLATINUM COMPLEX, AND MODULATOR OF CONTROL POINTS OF IMMUNE RESPONSE Russian patent published in 2022 - IPC A61K31/282 A61K31/513 A61K31/7072 A61K39/395 A61P35/00 

FIELD: medicine.

SUBSTANCE: group of inventions relates to the field of medicine, namely to a combination intended for the use in the treatment of colon and rectum cancer or gastrointestinal tract cancer, containing: a drug trifluridine-tipiracil hydrochloride (hereinafter – FTD-TPI), an antitumor platinum complex, which is oxaliplatin, and a modulator of control points of an immune response, which is nivolumab. The invention also relates to a drug intended for the use in the treatment of colon and rectum cancer or gastrointestinal tract cancer, containing, separately or together: a drug FTD-TPI, an antitumor platinum complex, which is oxaliplatin, and a modulator of control points of an immune response, which is nivolumab, intended for simultaneous or sequential use, where each component is provided in effective amount for the treatment of cancer.

EFFECT: group of inventions provides for the development of a new method for the treatment of gastrointestinal tract cancer.

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