FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to the chemical and pharmaceutical industry and is a method of enhancing the antitumour effect of an antitumour platinum complex and methods for treating a tumour, comprising: administering an antitumour platinum complex and a combination drug containing trifluridine and tipiracil hydrochloride in a molar ratio of 1:0.5, in combination to a mammal, where the daily dose of the combined drug on the day of administration of the combination drug is 50–100 % of the recommended dose of the combination drug for use in monotherapy and the daily dose of the antitumour platinum complex on the day of the administration of the antitumour platinum complex is 50–100 % of the recommended dose of the antitumour platinum complex for use in monotherapy, where the antitumour platinum complex is cisplatin, carboplatin or oxaliplatin, and where the malignant tumour being treated is a malignant tumour of the digestive system or lung cancer.
EFFECT: group of inventions describes new methods of treating malignant tumours with the use of a combination drug, which to a large extent has excellent antitumour effects with fewer side effects.
8 cl, 14 dwg, 7 tbl, 3 ex
