DOSING SCHEMES AND CORRESPONDING COMPOSITIONS AND METHODS Russian patent published in 2022 - IPC A61K38/10 A61K47/60 A61P37/00 

Abstract RU 2779495 C2

FIELD: medicine.

SUBSTANCE: methods for the treatment of a subject, who needs the treatment of a complement-mediated disorder, are proposed, including the administration of a long-acting compstatin analogue (hereinafter – LACA) containing PEG with an average molecular weight of 40 kDa, subcutaneously at a dose of 1080 mg. A single dosed composition of LACA containing PEG with an average molecular weight of 40 kDa is proposed for the treatment of a complement-mediated disorder in a subject for subcutaneous administration in the amount of 1080 mg. A device is proposed for delivery of a drug containing the specified single dosed composition.

EFFECT: proposed group of inventions provides for increase in doses of a long-acting compstatin analogue containing 40 kDa of PEG.

27 cl, 28 dwg, 23 tbl, 30 ex

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RU 2 779 495 C2

Authors

Grossi, Federiko

Deshatelets, Paskal

Fransua, Sedrik

Dzhonson, Patrik

Vega, Karolina

Dates

2022-09-07Published

2018-04-09Filed