FIELD: medicine.
SUBSTANCE: methods for the treatment of a subject, who needs the treatment of a complement-mediated disorder, are proposed, including the administration of a long-acting compstatin analogue (hereinafter – LACA) containing PEG with an average molecular weight of 40 kDa, subcutaneously at a dose of 1080 mg. A single dosed composition of LACA containing PEG with an average molecular weight of 40 kDa is proposed for the treatment of a complement-mediated disorder in a subject for subcutaneous administration in the amount of 1080 mg. A device is proposed for delivery of a drug containing the specified single dosed composition.
EFFECT: proposed group of inventions provides for increase in doses of a long-acting compstatin analogue containing 40 kDa of PEG.
27 cl, 28 dwg, 23 tbl, 30 ex
Title |
Year |
Author |
Number |
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|
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|
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|
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