1,9-(2'-HYDROXYMETHYL-1',4'-DIOXANO)-1,9-DIHYDRO-(C-I)[5,6]FULLERENE AND ITS PRODUCTION METHOD Russian patent published in 2022 - IPC C07D319/14 C01B32/152 C01B32/154 

Abstract RU 2785546 C2

FIELD: organic chemistry.

SUBSTANCE: invention relates to the field of organic chemistry of heterocyclic compounds, in particular, to development of a precursor of antiviral and hepatotoxic preparations. 1,9-(2'-hydroxymethyl-1',4'-dioxano)-1,9-dihydro-(C60-Ih)[5,6]fullerene of the formula (1) is disclosed. In addition, a method for the production of the above-mentioned compound is disclosed, different in that fullerene C60 interacts with glycerin in the presence of LiOH, at a molar ratio of C60 : glycerin : LiOH equal to 1:10-10,000:9-20, on air, at 50-100°C, in a medium of toluene : DMF = 1:0.5 (volumetric ratio), for 1-2 h.

EFFECT: invention provides a precursor in the manufacture of antiviral and hepatotoxic preparations.

2 cl, 1 tbl, 1 ex

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RU 2 785 546 C2

Authors

Kinzyabaeva Zemfira Sabitovna

Dates

2022-12-08Published

2021-05-20Filed