FIELD: veterinary medicine.
SUBSTANCE: vaccine composition for immunization and/or protection of a mammal – a dog, a cat, or a horse – from a disease mediated by IL-31 is proposed, where the specified composition contains a combination of a polypeptide carrier and at least one mimotope of peptide IL-31, and an adjuvant. Mimotope of peptide IL-31 has a length from about 5 to about 40 amino acids, and it is selected from a group consisting of mimotope of dog IL-31, mimotope of cat IL-31, mimotope of horse IL-31, and mimotope of human IL-31. A method for protection of a mammal from a disease mediated by IL-31 is presented. The method includes administration to a mammal of the presented vaccine composition.
EFFECT: invention allows for obtaining a vaccine for reduction in skin itch and skin damage in dogs, cats, horses with atopic dermatitis.
20 cl, 39 dwg, 2 ex
Title | Year | Author | Number |
---|---|---|---|
MONOCLONAL ANTIBODIES TO INTERLEUKIN-31 FOR VETERINARY USE | 2019 |
|
RU2795411C2 |
ANTI-IL31 ANTIBODIES FOR USE IN VETERINARY SCIENCE | 2020 |
|
RU2835543C1 |
ANTI-IL31 ANTIBODIES FOR VETERINARY USE | 2018 |
|
RU2795485C2 |
IL4 RECEPTOR ANTIBODIES FOR USE IN VETERINARY SCIENCE | 2019 |
|
RU2837141C2 |
CANINE ALPHA INTERLEUKIN-4 RECEPTOR ANTIBODIES | 2020 |
|
RU2840044C1 |
CANINE ALPHA INTERLEUKIN-4 RECEPTOR ANTIBODIES | 2020 |
|
RU2838943C1 |
PARVOVIRUS ANTIBODIES FOR USE IN VETERINARY SCIENCE | 2020 |
|
RU2830441C2 |
IL4/IL13 RECEPTOR MOLECULE FOR VETERINARY USE | 2018 |
|
RU2795591C2 |
VERSIONS OF Fc-REGION WITH ALTERED BINDING TO NEONATAL Fc-RECEPTOR (FcRn) FOR USE IN VETERINARY SCIENCE | 2019 |
|
RU2830231C2 |
IMMUNOCYTOKINES AND THEIR USE | 2021 |
|
RU2818371C1 |
Authors
Dates
2022-12-21—Published
2019-03-18—Filed