FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, in particular to an antibody capable of binding to canine IL4R and feline IL4R, and its antigen-binding fragment, as well as to a bispecific antibody containing same. Also disclosed is an isolated nucleic acid coding said antibody. Invention also relates to a method of detecting IL4R in a sample obtained from a companion animal species, involving the use of said antibody.
EFFECT: invention is effective for use in a method of treating a companion animal having an IL4/IL13-induced condition.
24 cl, 9 dwg, 11 tbl, 21 ex
| Title | Year | Author | Number |
|---|---|---|---|
| IL4/IL13 RECEPTOR MOLECULE FOR VETERINARY USE | 2018 |
|
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|
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|
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|
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| CANINIZED ANTI-HUMAN CTLA-4 ANTIBODIES | 2020 |
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| CANINE ALPHA INTERLEUKIN-4 RECEPTOR ANTIBODIES | 2020 |
|
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| PARVOVIRUS ANTIBODIES FOR USE IN VETERINARY SCIENCE | 2020 |
|
RU2830441C2 |
| CANINE ALPHA INTERLEUKIN-4 RECEPTOR ANTIBODIES | 2020 |
|
RU2838943C1 |
