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(19)

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2 786 722

(13)

(51)

IPC

C07K5/62(2006-01-01)

C07D403/12(2006-01-01)

A61K31/403(2006-01-01)

A61K38/05(2006-01-01)

A61P31/14(2006-01-01)

(21) (22)

Application

2021132570, 2021-08-06

(24)

Start date

2021-08-06

(22)

Actual filing date

2021-08-06

(45)

Published

2022-12-26

(72)

Inventor

Owen, Dafydd RhysPettersson, Martin YoungjinReese, Matthew RichardSammons, Matthew ForrestTuttle, Jamison BryceVerhoest, Patrick RobertWei, LiuqingYang, XiaojingYang, Qingyi

(73)

Holder

Pfizer Inc.

NITRILE-CONTAINING ANTIVIRAL COMPOUNDS Russian patent published in 2022 - IPC C07K5/62 C07D403/12 A61K31/403 A61K38/05 A61P31/14

Abstract RU 2786722 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidine-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, a solvate or hydrate thereof, pharmaceutical compositions containing said compound, and to a method for treating a coronavirus infection such as COVID-19.

EFFECT: creation of new compounds for treating a coronavirus infection.

26 cl, 15 dwg, 41 tbl, 98 ex

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RU 2 786 722 C1

Authors

Owen, Dafydd Rhys

Pettersson, Martin Youngjin

Reese, Matthew Richard

Sammons, Matthew Forrest

Tuttle, Jamison Bryce

Verhoest, Patrick Robert

Wei, Liuqing

Yang, Xiaojing

Yang, Qingyi

Dates

2022-12-26—Published

2021-08-06—Filed