FIELD: medicine.
SUBSTANCE: medicine, prevention and treatment of diseases of the urinary system. Invention relates to pharmaceutics, namely to a method for producing a diuretic and natriuretic agent in the form of sachet granules by wet granulation. A method of obtaining an agent with diuretic and natriuretic activity in the form of sachet granules by wet granulation, for which 94.5 g of sorbitol are crushed, then 0.5 g of ascorbic acid, 5.0 g of dry strawberry leaf extract are added, thoroughly mixed, dry mixture is moisten with 3 ml of ethyl alcohol 70%, adding it in small portions with constant stirring, the wet mass is wiped in a granulator, the granulate is dried at a temperature of 20–25°C to a residual moisture content of 2±0.5%.
EFFECT: obtaining a new agent with diuretic and natriuretic activity, having the required technological parameters.
1 cl, 1 dwg, 2 tbl, 1 ex
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Authors
Dates
2023-03-13—Published
2022-07-12—Filed