DOSING STRATEGY REDUCING CYTOKINE RELEASE SYNDROME FOR CD3/C20 BISPECIFIC ANTIBODIES Russian patent published in 2023 - IPC C07K16/28 A61K31/573 A61K39/00 A61P35/00 

Abstract RU 2799529 C2

FIELD: biotechnology.

SUBSTANCE: group of inventions is described, including a method for administering a therapeutic protein to a subject according to a dosing schedule to reduce the incidence or severity of cytokine release syndrome or an infusion reaction in the treatment of CD20-expressing B-cell lymphoma (versions) and a method of the treatment of CD20-expressing B-cell lymphoma in a subject.

EFFECT: invention expands the arsenal of methods of the treatment of CD20-expressing B-cell lymphoma.

84 cl, 1 dwg, 10 tbl, 2 ex

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RU 2 799 529 C2

Authors

Brownstein, Carrie

Lowy, Israel

Adriaens, Lieve Lucille

Dates

2023-07-05Published

2019-08-30Filed