FIELD: medicine.
SUBSTANCE: present group of inventions refers to therapy, and concerns treating the diseases mediated by expression of subtilisin/kexin 9 (PCSK9) type protoprotein convertase. That is ensured by administering a pharmaceutical composition containing an antibody which binds specifically to a protoprotein convertase hPCSK9, or an antigen-binding fragment thereof. Pharmaceutical composition contains said antibody in fixed doses — 75, 150 or 300 mg. Composition is administered once every two or four weeks.
EFFECT: such mode of administration provides effective treatment of said diseases or pathological conditions with minimal side effects.
24 cl, 6 dwg, 2 tbl, 4 ex
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