METHOD OF PRODUCING A MEDICINAL PRODUCT FOR THE TREATMENT OF ACUTE POSTPARTUM ENDOMETRITIS IN COWS Russian patent published in 2023 - IPC A61K31/165 A61K31/192 A61K31/245 A61K31/65 A61K36/896 A61K47/10 A61K125/00 A61P15/02 A61P31/10 

Abstract RU 2801945 C1

FIELD: veterinary medicine.

SUBSTANCE: invention relates to a method of producing a medicinal product with a pronounced anti-inflammatory, antiseptic and antifungal effect. A method of producing a medicinal product for the treatment of acute postpartum endometritis in cows, including the preparation of solutions of florfenicol and an antifungal active substance, the use of propylene glycol and purified water as a solvent, characterized in that an additional tetrachloride solution containing 4 g/l of the active substance and a florfenicol solution containing 4 g/l of the active substance, and as an anti-flexible active substance, a 3% aqueous solution of a mixture of sodium benzoate and potassium sorbate is used, which are taken in equal proportions, then all solutions are combined in equal amounts, novocaine, hellebore tincture are added and the resulting mixture is heated to 55–60°C followed by intensive stirring of this mixture in the reactor at a speed of 1,500 rpm, with the following ratio of components, wt.%: florfenicol solution containing 4 g/l of active substance 3, tetrachloride solution containing 4 g/l of active substance 3, 3 % aqueous solution of a mixture of sodium benzoate and potassium sorbate, taken in equal proportions 3, novocaine 1, hellebore tincture 1, purified water 15, propylene glycol is the rest.

EFFECT: increasing the therapeutic effect by enhancing the impact on opportunistic microflora, reducing the duration of treatment and costs.

1 cl, 2 tbl, 3 ex

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RU 2 801 945 C1

Authors

Nazarov Mikhail Vasilevich

Gavrilov Boris Viktorovich

Mashyanova Svetlana Yurevna

Limareva Mariya Aleksandrovna

Dates

2023-08-21Published

2022-08-03Filed