LIQUID SYMBIOTIC AND METHOD FOR OBTAINING IT Russian patent published in 2023 - IPC C12N1/20 A61K35/74 

Abstract RU 2805957 C1

FIELD: biotechnology.

SUBSTANCE: liquid symbiotic containing at least 108 CFU/ml of living microbial cells Bifidobacterium bifidum 1, Bifidobacterium bifidum 791, Bifidobacterium longum 379, Lactiplantibacillus plantarum 8RA-3, Limosilactobacillus fermentum 39, Limosilactobacillus fermentum 90TC-4, Escherichia coli M-17 and products of their metabolism, including neurometabolites, is proposed. A method for producing symbiotics from producer strains cultivated on a hydrolyzate-casein nutrient medium containing casein hydrolysate, sodium chloride, peptone, fructose, agar-agar, and ascorbic acid, is proposed. Three generations of producer strains are separately cultivated. The resulting three generations of biomass producer strains are mixed.

EFFECT: method makes it possible to obtain a liquid symbiotic with a wide spectrum of physiological effects and a high level of neurometabolites.

2 cl, 8 tbl, 1 ex

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RU 2 805 957 C1

Authors

Soloveva Irina Vladlenovna

Belova Irina Viktorovna

Tochilina Anna Georgievna

Zajtseva Natalya Nikolaevna

Molodtsova Svetlana Borisovna

Zhirnov Vladimir Anatolevich

Blagonravova Anna Sergeevna

Galova Elena Anatolevna

Mukhina Irina Vasilevna

Shirokova Irina Yurevna

Shchelchkova Natalya Aleksandrovna

Galova Darya Andreevna

Dates

2023-10-24Published

2022-11-22Filed