FIELD: pharmaceuticals.
SUBSTANCE: method for treating non-small-cell lung cancer (NSCLC) in a patient, including the administration of MEDI4736 and tremelimumab, where (i) the administration can give an average Cmax with a value of 266-300 μg/ml MEDI4736 and Cmax with a value of 25-30 μg/ml tremelimumab; (ii) MEDI4736 is administered 1 hour after tremelimumab administration and (iii) MEDI4736 and tremelimumab are administered every 4 weeks for a maximum of 16 weeks.
EFFECT: safety and synergistic effectiveness of the combination.
9 cl, 37 dwg, 9 tbl, 9 ex
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Authors
Dates
2023-10-30—Published
2015-05-12—Filed