ANTIBODIES TO B7-H1 FOR TREATING TUMOURS Russian patent published in 2024 - IPC A61K39/395 C07K16/28 G01N33/574 A61P35/00 

Abstract RU 2817281 C2

FIELD: medicine.

SUBSTANCE: invention relates to biochemistry, particularly to methods of treating tumours that express B7-H1, providing for the introduction of an effective amount of MEDI4736 or its antigen-binding fragment.

EFFECT: invention provides effective treatment of tumours by blocking B7-H1 binding with both PD-1 and CD80 receptors.

15 cl, 25 dwg, 19 tbl, 4 ex

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RU 2 817 281 C2

Authors

Narwal, Rajesh

Fairman, David

Robbins, Paul

Liang, Meina

Schneider, Amy

Chaves, Carlos

Herl, Carina

Pak, Min

Lu, Hong

Rebelatto, Marlon

Steele, Keith

Boutrin, Anmarie

Shi, Li

Hong, Shengyan

Higgs, Brandon

Roskos, Lorin

Dates

2024-04-12Published

2014-09-11Filed