FIELD: medicine.
SUBSTANCE: invention relates to biochemistry, particularly to methods of treating tumours that express B7-H1, providing for the introduction of an effective amount of MEDI4736 or its antigen-binding fragment.
EFFECT: invention provides effective treatment of tumours by blocking B7-H1 binding with both PD-1 and CD80 receptors.
15 cl, 25 dwg, 19 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
ANTIBODIES TO B7-H1 FOR TREATING TUMOURS | 2014 |
|
RU2701327C2 |
ANTIBODIES TO B7-H1 AND TO CTLA-4 FOR TREATING NON-SMALL-CELL LUNG CANCER | 2015 |
|
RU2702332C2 |
ANTIBODIES TO B7-H1 AND CTLA-4 FOR THE TREATMENT OF NON-SMALL CELL LUNG CANCER | 2015 |
|
RU2806210C2 |
COMBINATION OF PD-1 ANTAGONIST AND IDO1 INHIBITOR FOR TREATING ANCER | 2015 |
|
RU2744880C1 |
TREATING LUNG CANCER BY COMBINATION OF ANTI-PD-1 AND OTHER ANTI-CANCER AGENTS | 2015 |
|
RU2695332C2 |
COMBINATION OF ANTI-PD-L1 ANTIBODY AND DNA-PK INHIBITOR FOR TREATING MALIGNANT NEOPLASM | 2018 |
|
RU2765997C2 |
COMBINATION | 2015 |
|
RU2744841C2 |
METHODS OF TREATING CANCER USING PD-1 AND PD-L1 ANTAGONISTS IN COMBINATION WITH RADIATION THERAPY | 2015 |
|
RU2711408C2 |
TREATING CANCER WITH COMBINATION OF PD-1 ANTAGONIST AND DINACICLIB | 2014 |
|
RU2705795C2 |
PD-1/PD-L1 INHIBITORS FOR TREATING CANCER | 2016 |
|
RU2742312C1 |
Authors
Dates
2024-04-12—Published
2014-09-11—Filed