KIT FOR DETECTING ANTIBODIES OF CLASSES M AND G AGAINST NUCLEOCAPSID (Nc) AND RECEPTOR-BINDING DOMAIN OF SPIKE PROTEIN OF SARS-CoV-2 CORONAVIRUS Russian patent published in 2023 - IPC C12N15/00 C12Q1/6806 G01N33/569 

FIELD: biotechnology.

SUBSTANCE: kit for detecting antibodies of classes M and G to the nucleocapsid (Nc) and the receptor-binding domain of the spike protein of the SARS-CoV-2 coronavirus in a sample of human biological fluid is described. The kit contains an absorbent membrane for applying a sample and a membrane for applying a conjugate with applied and dried conjugates of the recombinant coronavirus antigen SARS-CoV-2, where the membrane for the sample is impregnated with a buffer solution, which is an aqueous solution prepared from the components in the following ratio, wt. %: tris-hydroxymethyl aminomethane 1%, tris-hydroxymethyl aminomethane hydrochloride 0.1%, sodium caseinate salt 1%, polyvinylpyrrolidone 0.1%, sodium azide 2%, tween-20 1%, mouse antibodies against human erythrocytes 0.02 %, the membrane for the conjugate is impregnated with an aqueous solution prepared from the components in the following ratio, wt. %: anhydrous sodium hydrogen phosphate 1.5%, polyvinyl alcohol 0.5%, bovine serum albumin 1%, Triton-X-100 0.1%, sodium azide 2%.

EFFECT: obtaining an accurate diagnostic result while using the invention.

1 cl, 3 dwg, 11 tbl, 3 ex