COMPOSITIONS FOR TOPICAL APPLICATION CONTAINING PICHIA ANOMALA AND RETINOL Russian patent published in 2024 - IPC A61K8/67 A61K8/9728 A61Q17/00 A61Q19/08 

FIELD: cosmetic industry.

SUBSTANCE: group of inventions relates to a composition for topical application to human skin to increase the amount of hyaluronic acid produced by the skin and to a method of increasing the amount of hyaluronic acid produced by the skin. A composition for topical application to human skin to increase the amount of hyaluronic acid produced by the skin, containing a 5% aqueous solution of Pichia anomala extract, with the content of Pichia anomala extract in the composition from 0.065 to 0.26% by weight, and from 0.05 to 1% by weight of retinol, while the weight ratio of Pichia anomala extract and retinol in the composition for topical application is 1.3. A method of increasing the amount of hyaluronic acid produced by the skin upon contact with an extract of Pichia anomala, comprising bringing the skin into contact with a composition for topical application according to claim 1.

EFFECT: above composition effectively increases the amount of hyaluronic acid produced by the skin and stimulates the expression of HAS2, CD44.

6 cl, 7 tbl, 3 ex