FIELD: biotechnology.
SUBSTANCE: described is a group of inventions comprising a monoclonal antibody that binds to tetanus toxin, use of a monoclonal antibody in the manufacture of a drug for preventing or treating tetanus and a method for preventing or treating tetanus, involving administering said monoclonal antibody to a subject. In one embodiment, the monoclonal antibody comprises a heavy chain variable region amino acid sequence selected from SEQ ID NO: 15–17, and the amino acid sequence of the light chain variable region SEQ ID NO: 18.
EFFECT: invention extends the range of tetanus toxin-binding agents.
4 cl, 9 dwg, 2 tbl, 11 ex
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Authors
Dates
2024-03-13—Published
2020-11-19—Filed