FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, namely to an antibody or an antigen-binding fragment thereof, which binds to thymic stromal lymphopoietin (TSLP), to a conjugate, a bispecific antibody, a pharmaceutical composition and a kit containing said conjugate, as well as to a method for production thereof. Also disclosed is an isolated nucleic acid molecule coding said antibody, as well as a cell and a vector containing same.
EFFECT: invention is effective for treating or preventing allergic inflammation or autoimmune disease in a patient, as well as for detecting the presence or level of TSLP in a sample.
47 cl, 9 dwg, 18 tbl, 22 ex
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Authors
Dates
2025-02-04—Published
2020-12-08—Filed