FIELD: veterinary virology; biotechnology.
SUBSTANCE: culturally inactivated sorbed vaccine against foot and mouth disease has been proposed. The vaccine consists of an active substance in the form of avirulent and purified antigenic material from SAT-2/Kenya/19/2017 strain SAT-2/IV genotype homologous to the causative agent of the infection, deposited in the All-Russian State Collection of Exotic Types of Foot-and-Mouth Disease Virus and Other Animal Pathogens (GKSHM) Federal State Budgetary Institution “Federal Centre for Animal Health” (FSBI “ARRIAH”), under registration number: No. 452-dep/23-2 - GKSHM FSBI “ARRIAH”, reproduced in VNK-21/SUSP/ARRIAH continuous suspension cell line, in an amount of at least 4.5 mcg; from aluminium hydroxide adjuvant - 10% colloidal solution containing 47% by volume, 4.7% in terms of dry matter, saponin in the amount of 1.8 mg, supporting medium — up to 2.0 cm3.
EFFECT: vaccine is highly immunogenic and can provide effective protection against a homologous infectious agent circulating in African and Middle East countries.
3 cl, 1 dwg, 7 tbl, 14 ex
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