FIELD: biotechnology.
SUBSTANCE: invention relates to the development of a cultured inactivated adsorbed vaccine against foot-and-mouth disease from O/Kenya/2017 strain of A/О/ЕА-2 new genotype. The vaccine contains an avirulent and purified concentrated antigen of O/Kenya/2017 strain of foot and mouth disease virus of A/О/ЕА-2 genotype, obtained in a suspension continuous cell line from the kidney of a newborn Syrian hamster (BHK-21/SUSP/ARRIAH), representing a suspension containing predominantly 146S immunogenic component of FMDV, adjuvant aluminum hydroxide and saponin in effective ratios. The vaccine is highly immunogenic and can provide effective protection against a homologous infectious agent circulating in African countries.
EFFECT: vaccine is relevant for ensuring biological safety for FMD in relation to the O/EA-2 genotype.
3 cl, 1 dwg, 8 tbl, 14 ex
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Authors
Dates
2023-08-22—Published
2023-03-21—Filed