FIELD: pharmaceutical chemistry.
SUBSTANCE: invention relates to pharmaceutical chemistry, specifically to 1,3,4-oxadiazole derivatives of deoxycholic acid of general formula I, where R=Py-4-yl, 4-Cl-C6H4. Said compounds have low toxicity, prostate-protective and anti-inflammatory action.
EFFECT: obtaining alternative compounds which reduce hyperplasia of glandular epithelium in the prostate gland, having anti-inflammatory activity and low toxicity, which can be used in medicine.
1 cl, 10 dwg, 5 tbl, 12 ex
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| 1,2,4-OXADIAZOLE DERIVATIVES OF DESOXYCHOLIC ACID, EXHIBITING PROSTATE-PROTECTIVE EFFECT, HYPOCHOLESTEROLEMIC AND ANTI-INFLAMMATORY ACTIVITY | 2020 |
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