FIELD: medicine.
SUBSTANCE: invention relates to treatment of estrogen-positive (ER+) forms of cancer. What is presented is using an elacestrant or a pharmaceutically acceptable salt or solvate thereof for inhibiting and reducing palbociclib-resistant, ribocyclib-resistant or abemacyclib-resistant estrogen receptor-alpha-positive cancer in a subject.
EFFECT: elacestrant has been shown to successfully inhibit growth of cancer cells which are resistant to palbociclib, ribociclib or abemaciclib.
19 cl, 2 ex, 52 dwg
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Authors
Dates
2024-06-04—Published
2019-12-06—Filed