METHODS OF TREATING CDK4/6 INHIBITOR-RESISTANT CANCER Russian patent published in 2024 - IPC A61K31/15 A61K31/137 A61K31/138 A61P35/00 

Abstract RU 2820478 C2

FIELD: medicine.

SUBSTANCE: invention relates to treatment of estrogen-positive (ER+) forms of cancer. What is presented is using an elacestrant or a pharmaceutically acceptable salt or solvate thereof for inhibiting and reducing palbociclib-resistant, ribocyclib-resistant or abemacyclib-resistant estrogen receptor-alpha-positive cancer in a subject.

EFFECT: elacestrant has been shown to successfully inhibit growth of cancer cells which are resistant to palbociclib, ribociclib or abemaciclib.

19 cl, 2 ex, 52 dwg

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RU 2 820 478 C2

Authors

Patel, Khitisha

Bikhani, Tiru

Arlt, Khajke

Tao, Niandzhun

Dates

2024-06-04Published

2019-12-06Filed