FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry, in particular to a monoclonal antibody capable of specifically binding to a human stabilin-1 receptor, namely to murine monoclonal antibodies against stabilin-1. Antibodies against human stabilin-1 receptor with high affinity with KD=2.23×10-12 M binds recombinant human stabilin-1 protein and native stabilin-1 on the surface of human macrophages, providing accumulation of antibodies in the tumour node.
EFFECT: invention can be effectively used for treating diseases associated with human stabilin-1.
1 cl, 4 dwg
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