METHYLTHIONINIUM AS COGNITIVE ENHANCER Russian patent published in 2024 - IPC A61K31/5415 A61P25/28 

Abstract RU 2824584 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine and can be used to stimulate cognitive function in a healthy individual. Disclosed is a method for stimulating cognitive function in a healthy individual, comprising administering to individual from 2 to 100 mg per day of methylthioninium (MT), optionally divided into 2 or more doses, where MT is administered in the form of a LMTX compound of the following formula , where each of HnA and HnB (when present) are protic acids, which may be the same or may be different, and where p = 1 or 2; q = 0 or 1; n = 1 or 2; (p + q) × n = 2 or a hydrate or solvate thereof; and wherein the LMTX compound stimulates basal levels of acetylcholine and synaptophysin in an individual.

EFFECT: invention provides activation of neuron function in healthy subjects by stimulating basal levels of choline and synaptophysin.

27 cl, 1 dwg, 2 tbl, 3 ex

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RU 2 824 584 C2

Authors

Riedel, Gernot

Klein, Jochen

Schwab, Karima

Wischik, Claude Michel

Harrington, Charles Robert

Dates

2024-08-12Published

2020-06-29Filed