FIELD: medicine.
SUBSTANCE: invention relates to ophthalmology and oncology, and can be used to determine the time of the first metastasis in uveal melanoma after eye enucleation. For this purpose, the presence or absence of ophthalmohypertension and intense staining of endothelial cells of uveal melanoma vessels is evaluated in a patient after eye enucleation by means of an immunohistochemical reaction with antibodies to VEGF. T-term of the first metastasis is calculated in months by the developed mathematical formula.
EFFECT: invention enables to accurately determine the time of the first metastasis at various times after enucleation, which in turn provides early diagnosis of the onset of metastases and timely treatment.
1 cl, 2 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTION OF SURVIVAL RATE AFTER ENUCLEATION WITH UVEAL MELANOMA DEVELOPED TO EQUATOR | 2024 |
|
RU2822319C1 |
METHOD PREDICTING CLINICAL COURSE OF UVEA MELANOMA BASED ON APOPTHOSIS MARKER p53 | 2002 |
|
RU2208789C1 |
METHOD OF PREDICTION OF CLINICAL COURSE OF UVEA MELANOMA BASED ON APOPTHOSIS MARKER Bax | 2002 |
|
RU2208790C1 |
METHOD OF SIMULTANEOUS VERIFICATION AND PREDICTION OF COURSE OF UVEAL MELANOMA | 2006 |
|
RU2337362C1 |
METHOD OF SIMULTANEOUS VERIFICATION OF UVEAL MELANOMA COURSE FORECAST | 2006 |
|
RU2327420C1 |
METHOD FOR PREDICTING METASTASES OF UVEAL MELANOMA BASED UPON APOPTOSIS MARKERS BAX AND BCL-2 | 2003 |
|
RU2242766C1 |
METHOD FOR PREDICTING UVEAL MELANOMA METASTASIS FORMATION ON THE BASIS OF BAX AND KI-67 MARKERS | 2003 |
|
RU2240560C1 |
METHOD FOR PREDICTING UVEAL MELANOMA METASTASIS SPREAD WITH APOPTOSIS MARKERS BAX AND BCL-2 | 2003 |
|
RU2244934C2 |
METHOD FOR PREDICTING CLINICAL FLOW OF UVEAL MELANOMA | 2001 |
|
RU2193200C1 |
METHOD FOR PREDICTING CLINICAL COURSE OF UVEAL MELANOMA DEVELOPMENT | 2001 |
|
RU2197731C2 |
Authors
Dates
2024-09-30—Published
2024-01-16—Filed