FIELD: medicine.
SUBSTANCE: invention refers to experimental toxicology. From the first day of the experiment, an aqueous solution of melatonin in dose of 5 mg/kg and an aqueous solution of cadmium sulphate in dose of 0.3 mg/kg in terms of metal are introduced through a probe into the stomach from the first day of the experiment.
EFFECT: method provides reducing the intensity of changes in the vascular-thrombocyte and coagulation haemostasis, restoring the activity of the anticoagulant and fibrinolytic blood systems, reduced degree of thrombinemia and oxidative stress, which in turn makes it possible to develop methods for prevention and pathogenetic correction of manifestations of toxic coagulopathy in rats with prolonged exposure to cadmium on the body.
1 cl, 5 tbl, 1 ex
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