METHOD FOR PREVENTION OF TOXIC COAGULOPATHY IN RATS Russian patent published in 2023 - IPC G09B23/28 A61K31/4045 A61P7/00 

Abstract RU 2794030 C1

FIELD: ecology; medicine; toxicology; experimental biology.

SUBSTANCE: invention can be used for the experimental development of methods for the prevention and pathogenetic correction of manifestations of toxic coagulopathy in rats with prolonged exposure to potassium bichromate. The method includes daily administration of an antioxidant and a heavy metal to rats. As an antioxidant, from the first day of the experiment, melaxen was introduced into the stomach through a tube at a dose of 5 mg/kg for two months. A solution of potassium dichromate is introduced as a heavy metal at a dose of 0.5 mg/kg in terms of metal.

EFFECT: invention provides reduction of pathological changes in indicators in the hemostasis system.

1 cl, 2 tbl, 1 ex

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RU 2 794 030 C1

Authors

Brin Vadim Borisovich

Gagloeva Elmira Muratovna

Dates

2023-04-11Published

2022-07-14Filed