FIELD: ecology; medicine; toxicology; experimental biology.
SUBSTANCE: invention can be used for the experimental development of methods for the prevention and pathogenetic correction of manifestations of toxic coagulopathy in rats with prolonged exposure to potassium bichromate. The method includes daily administration of an antioxidant and a heavy metal to rats. As an antioxidant, from the first day of the experiment, melaxen was introduced into the stomach through a tube at a dose of 5 mg/kg for two months. A solution of potassium dichromate is introduced as a heavy metal at a dose of 0.5 mg/kg in terms of metal.
EFFECT: invention provides reduction of pathological changes in indicators in the hemostasis system.
1 cl, 2 tbl, 1 ex
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Authors
Dates
2023-04-11—Published
2022-07-14—Filed