FIELD: chemistry; pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry, medicine and veterinary science. Disclosed acaricide ointment contains, wt.%: sodium 2,2'-(1E,1'E)-(butane-1,4-diylbis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-ylidene)dibenzene sulphonate of formula I – 0.2, methyluracil – 3.0, polyethylene oxide-400 – 25.0, polyethylene oxide-1500 – 71.8. Method of producing acaricide ointment consists in fact that 0.2 wt.% of sodium 2,2'-(1E,1'E)-(butan-1,4-diylbis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-ylidene)dibenzene sulphonate of formula I and 3.0 wt.% of methyluracil are taken, then 25.0 wt.% of polyethylene oxide-400 is added and stirred until complete dissolution at temperature of 60 °C, then in portions with slow stirring 71.8 wt.% of polyethylene oxide-1500 is added to the heated solution and stirred until complete dissolution, then temperature is raised to 100 °C and stirred for 30 minutes, then cooled to room temperature, prepared acaricide ointment is packaged in sterile bottles.
EFFECT: what is presented is an acaricide agent in the form of an ointment for treating parasitic diseases caused by scabies mites, and a method for preparing such an ointment.
2 cl, 7 tbl, 8 ex
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Authors
Dates
2024-12-09—Published
2024-04-27—Filed