SUBSTITUTED THIOPHENECARBOXAMIDES AND DERIVATIVES THEREOF AS MICROBIOCIDES Russian patent published in 2024 - IPC C07D333/38 C07D407/12 C07D409/12 A01N43/10 A01N43/36 A01N43/38 A01P1/00 A01P3/00 

Abstract RU 2832576 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula (I). In formula (I) R1 and R2 are identical and represent chlorine or bromine; R3 is methyl; R4 and R5 are independently selected from a group consisting of hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, C1-C6-alkoxy, C1-C6-haloalkyl, -C(=O)-OH, -O-C(=O)-C1-C6-alkyl, phenyl, 5-membered monocyclic heteroaryl containing 2 nitrogen heteroatoms, 9-membered bicyclic heteroaryl containing 1 nitrogen heteroatom, -C1-C6-alkyl-phenyl, -C1-C6-alkyl-S-C(=O)-C1-C6-alkyl, -C1-C6-alkyl-C(=O)-NH2, -C1-C6-alkyl-NH-C(=NH)-NH2, -C1-C6-alkyl-S-C(=O)-NH(C1-C6-alkyl), where acyclic R4, R5 radicals can be substituted with one or two Rw substitutes, where cyclic R4, R5 radicals can be substituted with one or two Rx substitutes, where at least one of R4 and R5 is hydrogen or C1-C6-alkyl, or R4 and R5 form together with the carbon atom to which they are attached, C3-C6-cycloalkyl or 4–6-membered heterocycle containing 1 heteroatom selected from the group consisting of oxygen and sulphur, where said C3-C6-cycloalkyl and 4–6-membered heterocycle can be substituted with one or two Rx substitutes, where Rw is independently selected from the group consisting of C3-C7-cycloalkyl, where Rx is independently selected from the group consisting of halogen, C1-C8-alkyl, C3-C7-cycloalkyl, C1-C8-haloalkyl having from 1 to 5 halogen atoms, C2-C8-alkenyl or C1-C8-alkoxycarbonyl; R6 and R7 are independently selected from a group consisting of hydrogen, C1-C6-alkyl, C3-C6-cycloalkyl; n is 0 or 1; W is oxygen or sulphur; Y is NR8, where R8 is hydrogen or C1-C6-alkyl; Z is selected from a group consisting of cyano, -C(=O)-ORa, -C(=O)-SRa, -C(=O)-NRbRc or -C(=O)-NH-CRdRe-C(=O)-ORa, where Ra is selected from a group consisting of hydrogen, C1-C6-alkyl, C3-C8-cycloalkyl, phenyl, -C1-C6-alkyl-phenyl, Rb and Rc are independently selected from the group consisting of hydrogen, C1-C6-alkyl, hydroxyl, C1-C6-alkoxy, C1-C6-cyanoalkyl, Rd and Re form together with a carbon atom to which they are attached, C3-C6-cycloalkyl; where, when W is oxygen, and Y is NH, and n = 0, and R4 is selected from the group consisting of hydrogen, C1-C6-alkyl, -C1-C6-alkyl-phenyl, and R5 is hydrogen, or R4 and R5 form, together with the carbon atom to which they are attached, cyclopropyl, then Z is selected from the group consisting of cyano, -C(=O)-SRa, -C(=O)-NRbRc, -C(=O)-NH-CRdRe-C(=O)-ORa; provided that ethyl{[(4,5-dibromo-3-methyl-2-thienyl)carbonyl]amino}(phenyl) acetate and ethyl{[(4,5-dichloro-3-methyl-2-thienyl)carbonyl]amino}(phenyl) acetate are excluded. Invention also relates to a composition containing said compound and use thereof for controlling bacterial and/or fungal diseases of plants.

EFFECT: invention can be used to combat bacterial and/or fungal diseases of plants.

10 cl, 56 tbl, 177 ex

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RU 2 832 576 C1

Authors

Dufour, Jeremy

Nicolas, Lionel

Knobloch, Thomas

Brunet, Stephane

Lamprecht, Sybille

Dates

2024-12-25Published

2020-12-17Filed