INDOLE COMPOUND, METHOD FOR PRODUCTION THEREOF AND USE THEREOF Russian patent published in 2025 - IPC C07D209/12 A61K31/405 A61P17/00 

Abstract RU 2838629 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula I, where W is COR2 or CR3R4OR5; X is absent or X is CO or CR3R4; Y is absent or Y is O; Z is absent or Z is CR3R4; R1 is selected from a group, consisting of unsubstituted C5-20alkyl, C6aryl substituted with 1-2 substitutes selected from acetoxy and chlorine, and fragment (a); R is H; each of R2, R3 and R4 is H; and R5 is H. Invention also relates to a compound where the compound is selected from a group of compounds presented in the formula, a pharmaceutical composition containing a compound of formula I or a compound selected from the group of compounds, and the use of a compound of formula I or a compound selected from a group of compounds in the manufacture of a medicament for the treatment of atopic dermatitis.

EFFECT: treatment of atopic dermatitis.

12 cl, 30 dwg, 11 tbl, 34 ex

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RU 2 838 629 C2

Authors

Xu, Xiaoqiang

Wang, Xiaokai

Ma, Yao

Zhong, Xianbin

Dates

2025-04-22Published

2022-09-02Filed