CRYSTALLINE FORM OF THIOPHENE DERIVATIVE AND METHOD FOR OBTAINING THEREOF Russian patent published in 2024 - IPC C07D333/70 A61K31/381 A61P19/06 

Abstract RU 2830948 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a crystalline form of a thiophene derivative selected from form C and E. Crystalline form C of the compound of formula (I) is characterized by a powder X-ray diffraction pattern containing characteristic diffraction peaks at the following values of angle 2θ: 13.20 ± 0.20°, 15.26 ± 0.20°, 18.08 ± 0.20°, 21.99 ± 0.20°, 25.07 ± 0.20°, 25.38 ± 0.20°, 26.66 ± 0.20°, 30.70 ± 0.20°. Crystalline form E of the compound of formula (I) is characterized by a powder X-ray diffraction pattern containing characteristic diffraction peaks at the following angle values 2θ: 9.11 ± 0.20°, 12.43 ± 0.20°, 13.28 ± 0.20°, 15.34 ± 0.20°, 18.16 ± 0.20°, 22.06 ± 0.20°, 23.15 ± 0.20°, 25.14 ± 0.20°.

EFFECT: crystalline forms C and E of the thiophene derivative of formula (I) for preparing a medicinal product for treating gout and hyperuricemia.

18 cl, 14 dwg, 15 tbl, 14 ex

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RU 2 830 948 C1

Authors

Zhang, Yang

Wu, Wentao

Li, Zhixiang

Zhu, Wenyuan

Dates

2024-11-26Published

2022-04-21Filed