FIELD: organic chemistry. SUBSTANCE: method of synthesis of 1,4-bis-(chlorocarbonyl)-piperazine involves interaction of piperazine hexahydrate with phosgene in medium of methylene chloride and water at decreased temperature at addition of soda ash to reaction mass. An aqueous solution of piperazine hexahydrate and soda ash is added to phosgene solution in methylene chloride at (-7)-(-20) C. EFFECT: increased yield, enhanced quality of product.
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREPARING POLYCARBPNATES | 0 |
|
SU704461A3 |
| 0 |
|
SU201428A1 | |
| METHOD OF PREPARING POLYCARBONATES | 0 |
|
SU592362A3 |
| METHOD OF PREPARING (1,4)-DITHIEPINO (2,3-C)-PYRROLE OR ITS SALTS | 0 |
|
SU869559A3 |
| METHOD OF PREPARING 1-NITROSO-4-METHYLPIPERAZINE | 1993 |
|
RU2095355C1 |
| METHOD OF PREPARING DITHIINO (1,4)(2,3,-C) PYRROL DERIVATIVES OR SALTS THEREOF | 0 |
|
SU576942A3 |
| METHOD OF PREPARING DERIVATIVES OF 1,4-DITHIEPINO-/2,3-C/-PYRROL OR THEIR SALTS | 0 |
|
SU856386A3 |
| METHOD OF PRODUCING 5,8-(BIS(METHYLENE(N,N-DIMETHYL-N-DODECYLAMMONIUM))-2-ETHYL-4H-[1,3]DIOXINO[4,5-C]PYRIDINIUM DICHLORIDE | 2019 |
|
RU2697848C1 |
| METHOD FOR PREPARATION OF L-ALANYL-L-PROLYN DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 0 |
|
SU1757471A3 |
| METHOD OF PREPARING 7-OXO-2,3,6,7-TETRAHYDRO-5H-OXATHIINO (1,4)(2,3-C) PYRROLE DERIVATIVES OR SALTS THEREOF | 0 |
|
SU576949A3 |
