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1 771 186

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A1

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IPC

(21) (22)

Application

4876943/04, 1990-10-23

(22)

Actual filing date

1990-10-23

(45)

Published

1995-11-10

(72)

Inventor

Klimova N.V.Karpova T.D.Karadzhaev Sh.Bykov N.P.Avdjunina N.I.Pjatin B.M.Morozov I.S.Pushkar' G.V.Zinov'Eva I.M.

PARA-CHLOROPHENOXYACETIC ACID ADAMANT-2-YLAMINOETHYL ESTER HYDROCHLORIDE SHOWING THERMOPROTECTIVE AND PSYCHOSTIMULATING ACTIVITIES Russian patent published in 1995 - IPC

Abstract SU 1771186 A1

FIELD: organic chemistry. SUBSTANCE: product: p-chlorophenoxyacetic acid adamant-2-ylaminoethyl ester hydrochloride, empirical formula is C20H27Cl2NO3, yield is 95.6%, m. p. is 222-223 C. Reagent 1: 2-β-hydroxyethylaminoadamantane hydrochloride. Reagent 2: p-chlorophenoxyacetic acid chloroanhydride. Reaction conditions: in the medium of anhydrous toluene at 120-125 C for 12 hr followed by addition of anhydrous toluene and ether saturated with hydrogen chloride to the cooled reaction mass. Synthesized compound is used as a medicinal preparation showing thermoprotective and psychostimulating action. EFFECT: improved method of synthesis. 3 tbl

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SU 1 771 186 A1

Authors

Klimova N.V.

Karpova T.D.

Karadzhaev Sh.

Bykov N.P.

Avdjunina N.I.

Pjatin B.M.

Morozov I.S.

Pushkar' G.V.

Zinov'Eva I.M.

Dates

1995-11-10—Published

1990-10-23—Filed

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