FIELD: clinical immunology. SUBSTANCE: method involves separating neutrophil fraction from venous heparinized blood by centrifuging at doubled density gradient of phycoll verografin, and determining elasticity of cell membranes by hemocytometer. Elasticity increased by 12-20% above standard value shows symptom of reduction of functional cell reserve while its increase by more than 20% points to total deactivation of polymorphous-nuclear leukocytes. EFFECT: higher informativeness of assessing functional disorders of polymorphous-nuclear leukocytes in case of purulent-septic infection by a single integral index, shorter time and less labor required for examination. 3 tbl
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