METHOD FOR PRODUCING 5-ARYL-2-HYDROXY-2- (TRIPHENYLPHOSPHARANILIDENE) -METHOXYCARBOBYLMETHYL-2,3- DIHYROFURANONES Russian patent published in 1994 - IPC

Abstract RU 2009144 C1

FIELD: medicine. SUBSTANCE: desired product 2-hydroxy-2-(triphenylphosphoranilidene) methoxycarbonylmethyl-5- phenyl-2,3-dihydro-3-furanone having structural formula I (image), empirical formula is C₃₁H₂₅O₅P, its decomposition temperature is 124-125 C its yield being 83% . Product 2-hydroxy-2- (triphenylphosphoranilidene) methoxycarbonylmethyl-5-p- chlorphenyl-2,3-dihydro-3 furanon having structural formula II (image), empirical formula is C₃₁H₂₄ClO₅P, its melting point is 163-164 C, its yield is 91% . Formula III (image) , where R= H, Cl is used as reagent 1, (C₆H₅)₃P=CHCOOCH₃ is used as reagent 2. Reaction is carried out at room temperature in the medium of inert organic solvent. Desired product have antimicrobial action. EFFECT: improves efficiency of the method.

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RU 2 009 144 C1

Authors

Koz'Minykh V.O.

Igidov N.M.

Koz'Minykh E.N.

Andrejchikov Ju.S.

Dates

1994-03-15—Published

1990-12-29—Filed