FIELD: virology. SUBSTANCE: for preparation of AIDS vaccine, antigen that is sequence 735-752 of viral capsid protein gp 41 is injected to animal. The antibodies produced are isolated and injected to another animal from which antibody- producing splenocytes are isolated to produce hybridomas. After incubation of the hybridomas, there is obtained an anti- idiotypic antibody that is capable of attaching to CD 4-cell marker-related epitope and inhibiting the binding between CD 4 cell marker and any of indicator antibodies Leu AAA and OKT AAAA. EFFECT: increased efficacy. 14 tbl
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