SYNTHETIC HIV PEPTIDE (VARIANTS), IMMUNOGENIC COMPOSITION FOR INDUCTION OF IMMUNE RESPONSE AGAINST HIV PEPTIDES, DIAGNOSTIC SET FOR ASSAY OF HIV-SPECIFIC ANTIBODIES Russian patent published in 2003 - IPC

FIELD: biotechnology, immunology, genetic engineering. SUBSTANCE: synthetic HIV peptide comprises amino acid sequence of T-cellular epitope of gag protein of immunodeficiency virus taken among P24N, P24L, P24M, P24H and P24E linked with amino acid sequence of B-cellular epitope of V3 loop of HIV isolate protein envelope containing the sequence GPGR or fused sequence of V3 loop from two different isolates of HIV-1, or containing consensus sequence of V3 loop of different isolates or linked with amino acid sequence of B-cellular epitope of protein gp41 of HIV isolate containing, in part, EZKDWA. Tetrameric form of synthetic HIV peptide comprises individual synthetic peptides with amino acid sequence of T-cellular epitope of protein gag of HIV isolate linked with the sequence of B-cellular epitope. Immunogenic composition comprising synthetic peptide induces immune response against HIV peptides. Diagnostic set for assay of HIV-specific antibodies involves synthetic peptide. Invention ensures to develop synthetic vaccines against HIV and can be used for preparing vaccine against HIV-infection. EFFECT: improved method of preparing, valuable biological and medicinal properties of peptide. 34 cl, 3 dwg, 14 tbl, 4 ex