FIELD: medicine.
SUBSTANCE: invention relates to immunology, and can be used to create a vaccine against HIV/AIDS. To do this, the immunogenic composition comprises synthetic peptides that mimic the consensus sequence of M V1-, V2-, V3 - loop and V3 - loop isolate Russia RU A022a2 casing HIV1 gp120 protein and peptide-loaded immunoadjuvant or dendritic cells.
EFFECT: use of the present invention is to provide an immunogenic composition elicits response to each antigen composition comprising synthetic peptides which replicate relevant antigenic determinants of HIV.
1 cl, 2 ex, 2 tbl
| Title |
Year |
Author |
Number |
| IMMUNOGENIC COMPOSITION CONTAINING SYNTHETIC PEPTIDES REPEATING SEQUENCE OF V3-LOOP OF SHELL PROTEIN GP120 HIV1 |
2017 |
- Korobova Svetlana Vyacheslavovna
- Aparin Petr Gennadevich
- Khaitov Rakhim Musaevich
|
RU2694576C2 |
| CHIMERIC PEPTIDE IMMUNOGENIC LIBRARY MIMICKING GENETIC DIVERSITY OF HYPERVARIABLE REGION OF PROTEIN V3 OF HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GP120 |
2002 |
- Maksjutov A.Z.
- Kolobov A.A.
- Ryzhikov A.B.
- Kanev A.N.
- Maksjutov Z.A.
|
RU2237065C2 |
| IMMUNOGENIC COMPOSITIONS OF GLYCOPROTEIN G OF HENDRA AND NIPAH VIRUSES |
2012 |
- Elhay, Martin
- Broder, Christopher, C.
- Huang, Jin-An
|
RU2787820C2 |
| VIRUS-LIKE PARTICLES WITH HIGH-DENSITY COATING FOR INDUCTION OF ANTIBODY EXPRESSION |
2017 |
- Carrillo Molina, Jorge
- Molinos-Albert, Luis, M.
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|
RU2813282C2 |
| IMMUNOGENS FOR VACCINATION AGAINST HIV |
2013 |
- Brander, Christian
- Mothe Pujadas, Beatriz
- Llano, Anuska
|
RU2721274C2 |
| RAPID SELECTION METHOD FOR HIV GP-120 VARIANTS |
2012 |
- Juste Errans Marija Eloiza
- Sanches Merino Viktor
- Ferrejra Karolina
|
RU2603732C2 |
| IMMUNOPROPHYLACTIC VACCINE AGAINST HIV BASED ON HIV-SPECIFIC ANTIBODIES |
2008 |
|
RU2505604C2 |
| NEW Tat-COMPLEXES AND VACCINES CONTAINING THEM |
2005 |
|
RU2432356C2 |
| HERPES VACCINE |
2019 |
- Al-Shekhadat Ruslan Ismailovich
- Simbirtsev Andrei Semenovich
|
RU2731073C1 |
| MURINE MONOCLONAL ANTIBODY NMO1, HYBRIDOMA CELLULAR LINE, FRAGMENT OF MURINE MONOCLONAL ANTIBODY (VARIANTS) |
1992 |
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