FIELD: organic chemistry. SUBSTANCE: product: 2-substituted 4-(3-tert. -butyl-4-hydroxyphenyl)thiazoline of formula (I) R1, where R2 - alkyl; (CH2)n-J-CR3R4 - hydrogen, alkyl, A-chain of formula: -CH=CR3-(CH2)m, CH=N-O-(CH2)n or R3; Y - a simple bond, oxygen, sulfur, carbonyl group; R4 and R5 - H, alkyl, n = 0-3, m = 1-4; Z - tetrazole, CN-group or a group of formula -C(= O)X, where X - hydroxy-residue of formula NR6R7 or R5, where C1-C3 - alkyl which can be substituted with hydroxyl, C1-C3-group or R6-alkylamine; R7 and H2N-C(=S)AZ - hydrogen, alkyl. Reagent 1: thiacarboxylic acid amide of formula 
. Reagent 2: halogen-1-phenylalkanone of formula (II) 
, where L - halogen. Synthesized compounds are used in medicine. EFFECT: improved method of synthesis. 7 tbl
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