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2 021 262

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C1

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IPC

(21) (22)

Application

5014207/04, 1991-07-02

(22)

Actual filing date

1991-07-02

(45)

Published

1994-10-15

(72)

Inventor

Miljutin A.V.Nazmetdinov F.Ja.Kolla V.Eh.Andrejchikov Ju.S.

(73)

Holder

Miljutin Aleksandr Vladimirovich

N-(5-BROMO-2-PYRIDYL)-AMIDE OF P-METHYLBENZOYLPYRUVIC ACID SHOWING ANTIINFLAMMATORY AND ANALGETIC ACTIVITY Russian patent published in 1994 - IPC

Abstract RU 2021262 C1

FIELD: organic chemistry. SUBSTANCE: product: N-(5-bromo-2-pyridyl)-amide of p-methylbenzoylpyruvic acid, empirical formula is C16H13BrN2O3, yield is 91%, m. p. is 225-226 C. Reagent 1: 5-bromo-2-aminopyridine. Reagent 2: 5-(p-methylphenyl)-2,3-dihydrofuran-2,3-dione. Reaction conditions: equimolar quantity of reagents, in absolute dioxane. Synthesized compounds are used in medicine as antiinflammatory and analgetic agents. EFFECT: improved method of synthesis. 1 tbl

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RU 2 021 262 C1

Authors

Miljutin A.V.

Nazmetdinov F.Ja.

Kolla V.Eh.

Andrejchikov Ju.S.

Dates

1994-10-15—Published

1991-07-02—Filed

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