FIELD: organic chemistry. SUBSTANCE: product of the formula (I) or its ester. Reagent 1: dimethyl ester of 5-deamino-2-(N',N'-dimethylaminomethylene)-amino-6-hydroxygrise- olic acid. Reagent 2: nitrite. Reaction conditions: in aqueous solution of acetic acid, at the room temperature. Synthesized compounds inhibit activity of phosphodiesterase. EFFECT: improved method of synthesis. 1 tbl
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Authors
Dates
1994-10-15—Published
1988-03-30—Filed