METHOD OF SYNTHESIS OF CEPHALOSPORIN DERIVATIVES OR THEIR SALTS Russian patent published in 1994 - IPC

Abstract RU 2024529 C1

FIELD: organic chemistry. SUBSTANCE: product - derivatives of cephalosporins of the formula (I) or their salts, such as additive salts with hydrohaloid acid. Reagent 1: compound of the formula (II) where R - protected aminogroup. Reagent 1 is cleavaged by amide bond. Reagent 1 is prepared by interaction of compound of the formula (III) or its salt with compound of the formula (IV) or its salt in the presence of ethyl-o-phenylphosphate. Synthesized compounds are used for synthesis of new antibiotics. EFFECT: improved method of synthesis. 2 cl, 1 tbl

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RU 2 024 529 C1

Authors

Akio Mijake[Jp]

Masakhiro Kondo[Jp]

Masakhiko Fudzino[Jp]

Dates

1994-12-15—Published

1990-09-21—Filed