HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION SHOWING ANTAGONISTIC ACTIVITY WITH RESPECT TO ANGIOTENSIN-II AND A METHOD OF ANTAGONIZATION OF ANGIOTENSIN-II IN MAMMALS Russian patent published in 1998 - IPC

Abstract RU 2104276 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to new derivatives of benzimidazole. Product: 1-[[2'-(2,5-dihydro-5- -oxo-1,2,4-oxadiazole-3-yl)-biphenyl-4-yl] -methyl]-2-propylbe- -nzimidazole-7-carboxylic acid, yield is 90%, m. p. is 169-171 C, empirical formula is $$$. The synthesized compounds can be used in medicine, in part, in therapy and cardiology. EFFECT: improved method of synthesis. 29 cl, 1 tbl

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RU 2 104 276 C1

Authors

Takekhiko Naka[Jp]

Esijuki Finada[Jp]

Dates

1998-02-10Published

1992-06-26Filed