FIELD: biotechnology. SUBSTANCE: method involves the cultivation of one of microorganism strain Streptomyces thermoarchaensis NCIB 12015, 12111, 12112, 12113 or 12114 under aerobic condition at 20-50 C and pH 5.5-8.5 for at least 2 days. Antibiotic is isolated from cultural fluid. Antibiotic formula is given in invention description. Antibiotic is purified by chromatography method if necessary. The end product shows antihelminthic activity. EFFECT: improved method of antibiotic preparing.
| Title | Year | Author | Number |
|---|---|---|---|
| MACROCYCLIC LACTONE, PHARMACEUTICAL COMPOSITION HAVING ANTIBIOTIC ACTIVITY AND INSECT-ACARICIDE COMPOSITION | 1992 |
|
RU2100354C1 |
| PROCESS FOR PREPARING MACROCYCLIC COMPOUNDS | 1988 |
|
RU2015981C1 |
| PROCESS FOR PREPARING MACROLIDIC COMPOUNDS | 1990 |
|
RU2029770C1 |
| MACROLIDE COMPOUNDS, COMPOSITION SHOWING ANTIBIOTIC ACTIVITY, VETERINARY COMPOSITION, INSECTICIDE-ACARICIDE-NEMATOCIDE COMPOSITION AND A METHOD OF INSECT AND/OR TICK AND NEMATODE KILLING | 1992 |
|
RU2099334C1 |
| METHOD OF PREPARING BL508-DELTA ANTIBIOTIC | 0 |
|
SU715034A3 |
| METHOD FOR PREPARATION OF ANTIBIOTIC @@@ AND STREPTOMYCETES STRAINS-PRODUCERS OF ANTIBIOTIC @@@ | 0 |
|
SU1738090A3 |
| METHOD OF OBTAINING ANTIBACTERIAL SUBSTANCE | 0 |
|
SU618053A3 |
| PROCESS FOR PRODUCING PROLONGED-RELEASE PILLS | 1990 |
|
RU2014832C1 |
| METHOD OF PRODUCING ANTIBIOTICS-AV290-BASED FODDER ADDITIVE | 0 |
|
SU1047377A3 |
| 0 |
|
SU469265A3 |
