STRAIN OF VIRUS ECHO TYPE 11 FOR SEROLOGICAL DIAGNOSIS OF ENTEROVIRAL UVEITIS IN CHILDREN Russian patent published in 1995 - IPC

Abstract RU 2031942 C1

FIELD: virology. SUBSTANCE: strain Mop/M of virus ECHO 11 is isolated in 1982 from urine of 3-month old girl with acute uveitis. Strain is deposited in State Collection of Virology Institute at number 2274. Strain Mop/M of virus ECHO 11 shows expressed ophthalmotropism in monkey experiments and represents antigen species of ECHO 11 virus. Strain Mop/M distincts by antigenicity from standard strain Gregory ECHO 11 virus and from ophthalmotropic strain Karim/A ECHO 11 virus in neutralization reaction. Strain Mop/M ECHO 11 virus is used as diagnostic antigen preparation in neutralization reaction for specific serological diagnosis of enteroviral uveitis in children. Detection in children with uveitis of obscure etiology of antibodies to the strain Mop/M at titer 1:64 and above (usually (1:512)-(1:2048)) is a laboratory proof of virus ECHO 11 involvement with eye disease which is related with strain Mop/M. EFFECT: detection of virus strain indicated above. 2 tbl

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RU 2 031 942 C1

Authors

Koroleva G.A.

Lashkevich V.A.

Savinov A.P.

Dates

1995-03-27Published

1992-03-17Filed