FIELD: pharmacology. SUBSTANCE: synthetic analogue of natural hydra morphogene showing amino acid sequence Gly-Pro-Pro-Gly-Gly-Ser-Arg-Val-Jle-Leu-Phe-OH is proposed as antiviral agent. Lethality is decreased from 80% to 20% viral disease course of extromelia in experiment is alleviated. Indicated peptide can be used as medicinal preparation. Effective doses (0.1-1 mcg/kg) have no by-side negative action. EFFECT: enhanced quality of agent proposed. 5 dwg, 1 tbl
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Authors
Dates
1995-09-10—Published
1992-06-11—Filed