BIOLOGICALLY ACTIVE PEPTIDES Russian patent published in 2016 - IPC C07K7/08 A61K38/10 A61P31/12 A61P35/00 A61P37/00 A61K49/14 

FIELD: chemistry.

SUBSTANCE: invention relates to biotechnology and particularly to synthetic peptides with immunostimulating properties, and can be used in medicine. A series of peptides is synthesised, the peptides differing on chemical structure from existing biologically active Alloferon and Allostatin peptides. The difference lies in that in position 6 of the His-Gly-Val-Ser-Gly-X-Gly-Gln-His-Gly-Val-His-Gly structure, instead of histidine or tryptophan typical for said peptides, there are other amino acids of the aliphatic and aromatic series, as well as chemical modifications thereof. The obtained peptides are used in an immunomodulating and antiviral pharmaceutical composition.

EFFECT: invention enables to obtain peptides which effectively induce production of interleukin-18 and interferon gamma.

2 cl, 4 tbl, 4 ex