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Application

4938187/04, 1991-05-20

(22)

Actual filing date

1991-05-20

(45)

Published

1995-09-10

(72)

Inventor

Kochinova O.F.Zubkova I.V.Chernykh V.P.Komissarov V.I.Pichugin V.V.Sidorenko A.F.Avdeeva E.V.

(73)

Holder

Kurskij Gosudarstvennyj Meditsinskij Institut

N-2-(-RR-5-RR-6-RR-BENZIMIDAZOLYL)-SUCCINAMIC ACIDS SHOWING NEUROLEPTIC, ANTIHYPOXIC AND ANTIARRHYTHMIC ACTIVITIES Russian patent published in 1995 - IPC

Abstract RU 2043344 C1

FIELD: organic chemistry. SUBSTANCE: product of the general formula where a) R1=CH3; R2=R3=Br; b) R1= H-C4H9; R2=R3=H. For a): m. p. is 142-143 C, empirical formula is C15H19N3O3, yield is 70% For b): m. p. is 309-310 C, empirical formula is C12H11N3O3,, yield is 65% Reagent 1: 2-amino-1-R1-5-R2-6-R3-benzimidazole. Reagent 2: succinic anhydride. Medium: dry dioxane. EFFECT: improved method of synthesis. 6 tbl

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RU 2 043 344 C1

Authors

Kochinova O.F.

Zubkova I.V.

Chernykh V.P.

Komissarov V.I.

Pichugin V.V.

Sidorenko A.F.

Avdeeva E.V.

Dates

1995-09-10—Published

1991-05-20—Filed

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